Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including nuclear retinoic acid receptor binding activity; transcription coregulator activity; and transcription coregulator binding activity. A structural constituent of presynaptic active zone. Involved in negative regulation of DNA-templated transcription; synaptic vesicle docking; and white fat cell differentiation. Acts upstream of or within cellular response to leukemia inhibitory factor; positive regulation of retinoic acid receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in nucleus and ribbon synapse. Part of transcription repressor complex. Is active in several cellular components, including photoreceptor ribbon synapse; presynaptic active zone cytoplasmic component; and presynaptic cytosol. Is expressed in several structures, including limb; lung; nervous system; sensory organ; and tooth. Orthologous to human CTBP2 (C-terminal binding protein 2).