Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and chromatin DNA binding activity. Involved in several processes, including DNA modification; gastrulation; and nervous system development. Acts upstream of or within several processes, including formation of primary germ layer; nervous system development; and trophectodermal cell differentiation. Located in nucleus. Part of chromatin. Is expressed in several structures, including brain; early conceptus; gonad; limb; and limb bud. Orthologous to human EOMES (eomesodermin).