Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables several functions, including enzyme binding activity; nucleic acid binding activity; and transcription corepressor binding activity. Involved in several processes, including gluconeogenesis; monocarboxylic acid metabolic process; and regulation of gene expression. Acts upstream of or within circadian rhythm and negative regulation of transcription by RNA polymerase II. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study advanced sleep phase syndrome 1. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome and advanced sleep phase syndrome 1. Orthologous to human PER2 (period circadian regulator 2).