Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to be a structural constituent of skin epidermis. Involved in defense response to other organism; morphogenesis of an epithelium; and wound healing. Acts upstream of or within Wnt signaling pathway; intermediate filament organization; and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in alimentary system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in focal or diffuse nonepidermolytic palmoplantar keratoderma and pachyonychia congenita. Orthologous to human KRT6A (keratin 6A); KRT6B (keratin 6B); and KRT6C (keratin 6C).