Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits integrin binding activity. Involved in several processes, including early endosome to late endosome transport; embryo implantation; and positive regulation of integrin-mediated signaling pathway. Localizes to several cellular components, including Golgi apparatus; apical plasma membrane; and membrane raft. Colocalizes with cytoplasmic vesicle and plasma membrane. Is expressed in several structures, including alimentary system; medulla oblongata lateral wall; naris epithelium; respiratory system; and ventricular layer. Used to study placental insufficiency. Human ortholog(s) of this gene implicated in nephrotic syndrome type 10. Orthologous to human EMP2 (epithelial membrane protein 2).