Automated description from the Alliance of Genome Resources
Exhibits integrin binding activity. Involved in several processes, including early endosome to late endosome transport; embryo implantation; and positive regulation of integrin-mediated signaling pathway. Localizes to the Golgi apparatus; apical plasma membrane; and cell surface. Colocalizes with the cytoplasmic vesicle; membrane raft; and plasma membrane. Used to study placental insufficiency. Human ortholog(s) of this gene implicated in nephrotic syndrome type 10. Is expressed in several structures, including alimentary system; medulla oblongata lateral wall; naris epithelium; respiratory system; and ventricular layer. Orthologous to human EMP2 (epithelial membrane protein 2).