GO Annotations Graph

• Symbol: Emp2
• Name: epithelial membrane protein 2
• ID: MGI:1098726

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005178	integrin binding	IPI	J:215661
Molecular Function	GO:0005178	integrin binding	ISO	J:103508
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Cellular Component	GO:0045177	apical part of cell	IDA	J:109419
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:215886
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:103508
Cellular Component	GO:0009986	cell surface	IDA	J:109419
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:103508
Cellular Component	GO:0005737	cytoplasm	IDA	J:215886
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:215661
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:109419
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:91398
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:215661
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IDA	J:91398
Cellular Component	GO:0045121	membrane raft	IDA	J:215657
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:215661
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0070252	actin-mediated cell contraction	ISO	J:164563
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0032060	bleb assembly	ISO	J:164563
Biological Process	GO:0043534	blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0045022	early endosome to late endosome transport	IDA	J:215886
Biological Process	GO:0007566	embryo implantation	IMP	J:109419
Biological Process	GO:0007566	embryo implantation	ISO	J:164563
Biological Process	GO:0060136	embryonic process involved in female pregnancy	IMP	J:243365
Biological Process	GO:0060914	heart formation	IMP	J:319835
Biological Process	GO:0001765	membrane raft assembly	IDA	J:91398
Biological Process	GO:0001787	natural killer cell proliferation	IMP	J:243365
Biological Process	GO:1990266	neutrophil migration	IMP	J:293323
Biological Process	GO:0044854	plasma membrane raft assembly	IMP	J:293323
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:243365
Biological Process	GO:0062043	positive regulation of cardiac epithelial to mesenchymal transition	IMP	J:319835
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	ISO	J:103508
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	ISO	J:103508
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	IMP	J:103508
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:293323
Biological Process	GO:0034394	protein localization to cell surface	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:215661
Biological Process	GO:0045765	regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0001952	regulation of cell-matrix adhesion	IDA	J:215661
Biological Process	GO:0010594	regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0003093	regulation of glomerular filtration	ISO	J:164563
Biological Process	GO:0043549	regulation of kinase activity	ISO	J:164563
Biological Process	GO:2001212	regulation of vasculogenesis	ISO	J:164563
Biological Process	GO:0001913	T cell mediated cytotoxicity	IDA	J:215657