Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable calcium-dependent cysteine-type endopeptidase inhibitor activity and protease binding activity. Involved in several processes, including egg activation; inhibition of cysteine-type endopeptidase activity; and negative regulation of type B pancreatic cell apoptotic process. Acts upstream of or within negative regulation of peptidase activity. Located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; gonad; immune system; lung; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease; autoimmune disease (multiple); congenital myasthenic syndrome 1A; and vasculitis. Orthologous to human CAST (calpastatin).