Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits several functions, including calcium channel regulator activity; calcium-dependent protein binding activity; and signaling receptor binding activity. Involved in several processes, including regulation of glutamate receptor signaling pathway; regulation of synapse organization; and synapse organization. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; axonal growth cone; and integral component of presynaptic active zone membrane. Predicted to colocalize with slit diaphragm. Is expressed in several structures, including adrenal gland; limb; nervous system; oral epithelium; and sensory organ. Used to study autism spectrum disorder and schizophrenia. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Orthologous to human NRXN1 (neurexin 1).