Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTPase activity. Involved in several processes, including alpha-beta T cell differentiation; negative regulation of oxidative phosphorylation; and regulation of cytoskeleton organization. Acts upstream of or within several processes, including nervous system development; positive regulation of organelle organization; and regulation of systemic arterial blood pressure by hormone. Located in several cellular components, including cytosol; lamellipodium; and ruffle membrane. Is expressed in several structures, including brain; exocrine system; genitourinary system; heart; and pericardial component. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A).