Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Localizes to extracellular space. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor).