Automated description from the Alliance of Genome Resources
Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; precursor B lymphoblastic lymphoma/leukemia; thrombophilia (multiple); and toxic shock syndrome. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Orthologous to human TFPI (tissue factor pathway inhibitor).