Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits centromeric DNA binding activity and damaged DNA binding activity. Predicted to contribute to dinucleotide repeat insertion binding activity; single guanine insertion binding activity; and single-stranded DNA binding activity. Involved in mismatch repair and somatic recombination of immunoglobulin gene segments. Predicted to localize to MutSbeta complex. Is expressed in early conceptus; oocyte; and secondary oocyte. Human ortholog(s) of this gene implicated in colorectal carcinoma; endometrial cancer; endometrial carcinoma; and familial adenomatous polyposis 4. Orthologous to human MSH3 (mutS homolog 3).