Automated description from the Alliance of Genome Resources
Exhibits centromeric DNA binding activity and damaged DNA binding activity. Predicted to contribute to dinucleotide repeat insertion binding activity; single guanine insertion binding activity; and single-stranded DNA binding activity. Involved in mismatch repair and somatic recombination of immunoglobulin gene segments. Predicted to localize to the MutSbeta complex. Human ortholog(s) of this gene implicated in colorectal carcinoma; endometrial cancer; endometrial carcinoma; and familial adenomatous polyposis 4. Is expressed in early conceptus; oocyte; and secondary oocyte. Orthologous to human MSH3 (mutS homolog 3).