Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable integrin binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; smooth muscle cell differentiation; and smooth muscle tissue development. Acts upstream of or within several processes, including inner ear morphogenesis; memory; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in apical part of cell. Is expressed in several structures, including alimentary system; brain; genitourinary system; inner ear; and intraembryonic coelom. Human ortholog(s) of this gene implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (integrin subunit alpha 8).