Automated description from the Alliance of Genome Resources
Predicted to have metal ion binding activity. Involved in several processes, including extracellular matrix organization; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; and positive regulation of transforming growth factor beta receptor signaling pathway. Localizes to the apical part of cell. Human ortholog(s) of this gene implicated in end stage renal failure; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (integrin subunit alpha 8).