Automated description from the Alliance of Genome Resources
Exhibits phosphatidylinositol 3-kinase binding activity and protein kinase binding activity. Involved in several processes, including insulin receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of insulin secretion. Localizes to the cytosol; plasma membrane; and protein-containing complex. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including brain ventricular layer; hindlimb digit skin; jaw; metanephros; and thymus primordium. Orthologous to human IRS2 (insulin receptor substrate 2).