Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits phosphatidylinositol 3-kinase binding activity and protein kinase binding activity. Involved in several processes, including insulin receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of insulin secretion. Localizes to cytosol; plasma membrane; and protein-containing complex. Is expressed in several structures, including brain ventricular layer; hindlimb digit skin; jaw; metanephros; and thymus primordium. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IRS2 (insulin receptor substrate 2).