Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits microtubule motor activity. Involved in several processes, including determination of left/right symmetry; epithelial cilium movement involved in extracellular fluid movement; and lateral ventricle development. Localizes to outer dynein arm. Is expressed in trachea epithelium. Used to study otitis media; primary ciliary dyskinesia (multiple); tetralogy of Fallot; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Orthologous to human DNAH5 (dynein axonemal heavy chain 5).