Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cellular response to starvation; positive regulation of biosynthetic process; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including insulin receptor signaling pathway; mRNA transcription by RNA polymerase II; and regulation of transcription by RNA polymerase II. Located in cytoplasm; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in coronary artery disease; disease of metabolism; and type 2 diabetes mellitus. Orthologous to human SREBF1 (sterol regulatory element binding transcription factor 1).