Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTP-dependent protein binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including dendritic spine morphogenesis; heart development; and positive regulation of cellular component organization. Acts upstream of or within several processes, including cellular response to type II interferon; filopodium assembly; and positive regulation of intracellular signal transduction. Located in several cellular components, including leading edge membrane; phagocytic vesicle; and storage vacuole. Is active in cell leading edge and glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Used to study cleft palate and microvillus inclusion disease. Human ortholog(s) of this gene implicated in fibrosarcoma. Orthologous to human CDC42 (cell division cycle 42).