Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits transcription coactivator activity and ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of Golgi lumen acidification; and reproductive structure development. Localizes to cytosol and nucleus. Is expressed in central nervous system and retina. Used to study Angelman syndrome. Human ortholog(s) of this gene implicated in Angelman syndrome. Orthologous to human UBE3A (ubiquitin protein ligase E3A).