Automated description from the Alliance of Genome Resources
Exhibits transcription coactivator activity and ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of phosphatidylinositol 3-kinase signaling; and reproductive structure development. Localizes to the cytosol and nucleus. Used to study Angelman syndrome. Human ortholog(s) of this gene implicated in Angelman syndrome. Orthologous to human UBE3A (ubiquitin protein ligase E3A).