Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits glutamate-cysteine ligase catalytic subunit binding activity. Involved in several processes, including cellular response to leukemia inhibitory factor; glutathione biosynthetic process; and positive regulation of glutamate-cysteine ligase activity. Localizes to glutamate-cysteine ligase complex. Human ortholog(s) of this gene implicated in myocardial infarction and vascular dementia. Is expressed in several structures, including alimentary system; liver; nervous system; urinary system; and yolk sac. Orthologous to human GCLM (glutamate-cysteine ligase modifier subunit).