Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including cellular response to leukemia inhibitory factor; hematopoietic or lymphoid organ development; and regulation of histone methylation. Localizes to the histone methyltransferase complex. Colocalizes with the ESC/E(Z) complex. Human ortholog(s) of this gene implicated in autistic disorder. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2).