Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein tyrosine phosphatase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; regulation of cell migration; and regulation of signal transduction. Acts upstream of or within heart development; oligodendrocyte differentiation; and vasculogenesis. Located in immunological synapse and ruffle membrane. Is expressed in midbrain; renal calyx; renal pelvis; and superior colliculus. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).