GO Annotations Graph

• Symbol: Ptprj
• Name: protein tyrosine phosphatase receptor type J
• ID: MGI:104574

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0045296	cadherin binding	ISO	J:164563
Molecular Function	GO:0070097	delta-catenin binding	ISO	J:164563
Molecular Function	GO:0045295	gamma-catenin binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:164563
Molecular Function	GO:0016791	phosphatase activity	ISO	J:164563
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005161	platelet-derived growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IMP	J:169798
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	IDA	J:169796
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:150385
Cellular Component	GO:0032587	ruffle membrane	IDA	J:150385
Biological Process	GO:0030183	B cell differentiation	IMP	J:131736
Biological Process	GO:0007596	blood coagulation	IMP	J:148960
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	IGI	J:131736
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0042593	glucose homeostasis	IMP	J:281561
Biological Process	GO:0007507	heart development	IMP	J:82356
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	IDA	J:169797
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:169798
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IMP	J:281561
Biological Process	GO:0043407	negative regulation of MAP kinase activity	IDA	J:169797
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	IBA	J:265628
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	IDA	J:169797
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:2000272	negative regulation of signaling receptor activity	IMP	J:169798
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	IDA	J:169796
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0043116	negative regulation of vascular permeability	ISO	J:164563
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:145866
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:164563
Biological Process	GO:1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	IMP	J:281561
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050918	positive chemotaxis	ISO	J:164563
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	IDA	J:169797
Biological Process	GO:1905451	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	IGI	J:131736
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	ISO	J:164563
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	IDA	J:150385
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGI	J:131736
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IGI	J:131736
Biological Process	GO:0010572	positive regulation of platelet activation	IMP	J:148960
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IGI	J:131736
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0001570	vasculogenesis	IMP	J:82356