Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits 1-phosphatidylinositol binding activity and Rho guanyl-nucleotide exchange factor activity. Involved in Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Localizes to lamellipodium and membrane. Is expressed in nervous system and retina. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).