Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 1-phosphatidylinositol binding activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Located in lamellipodium and membrane. Is expressed in liver; nervous system; retina; and testis. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).