Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including animal organ development; lymphoid lineage cell migration into thymus; and regulation of positive thymic T cell selection. Predicted to localize to the nucleus. Used to study DiGeorge syndrome and T-cell immunodeficiency, congenital alopecia, and nail dystrophy. Human ortholog(s) of this gene implicated in T-cell immunodeficiency, congenital alopecia, and nail dystrophy; alopecia; nail disease; and primary immunodeficiency disease. Is expressed in several structures, including 3rd branchial pouch; central nervous system; epithelium; gut gland; and integumental system. Orthologous to human FOXN1 (forkhead box N1).