Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including BMP receptor activity; PDZ domain binding activity; and activin binding activity. Involved in several processes, including Sertoli cell proliferation; copulation; and regulation of nitric-oxide synthase activity. Localizes to cell surface. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A).