Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription factor binding activity; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including nervous system development; placenta development; and positive regulation of transcription by RNA polymerase II. Localizes to intracellular and transcription regulator complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Used to study hypopituitarism. Human ortholog(s) of this gene implicated in panhypopituitarism. Orthologous to human LHX3 (LIM homeobox 3).