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Inbred Strains of Mice: PBA

PBA

Inbr: F20 +. Albino. Genet: c. Origin: P. C. Bailey from a pair of pet shop mice purchased in Birmingham, Alabama, in 1958.


Characteristics

Litter size 6.1; 6 week weight 21 g (both sexes); mean life-span 317 days in males, 268 days in females. Spontaneous lymphomas 100%, mammary tumours 74%, pulmonary adenomas 77% in animals over 1 year (Bailey et al., 1970., 1970). Development of spontaneous adenomas associated with increased serum concentration of IgG1 and IgG2 immunoglobulins (Schrohenloher and Bailey, 1972).


Bailey P. C., Leach W. B., and Hartley M. W. (1970) Characteristics of a new inbred strain of mice (PBA) with a high tumor incidence: preliminary report. J. Natl. Cancer Inst. 45, 59-73. \par

Schrohenloher R. E. and Bailey P. C. (1972) Atypical immunoglobulins associated with spontaneous lymphomas in an inbred strain of mice. J. Natl. Cancer Inst. 49, 1027-1037. \par


INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory