Inbred Strains
of Mice: NSY
Inbr F47 (Sept. 1996). Albino. Origin: From Jcl:ICR mice in 1975 with selective
breeding for glucose intolerance. Develop spontaneous non-insulin-dependent
diabetes mellitus in an age-dependent manner, reaching 98% in males and
31% in females at 48 weeks of age. Neither severe obesity nor extreme
hyperinsulinemia is seen at any age (
Ueda et
al, 1995).
Ueda H., Ikegami
H., Yamato E., Fu J., Fukuda M., Shen G., Kawaguchi Y., Takekawa K., Fujioka
Y., Fujisawa T., Nakagawa Y., Hamada Y., Shibata M., and Ogihara T. (1995)
The NSY mouse: A new animal model of spontaneous NIDDM with moderate obesity.
Diabetologia 38, 503-508.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK