of Mice: KE
Inbr:F94 (Kw). Genet: a, b, c, P.
Origin: Krzanowska 1952, from
mice of unknown origin; cross also produced KP.
Mean litter size 6.1; low percentage of fertilised ova. 17.6% of spermatozoa
have abnormal heads, the inheritance of this character being connected
to the Y chromosome and may be due to a rel. deficiency of androgens (Bartke and Krzanowska, 1972
). Sperm head
shape, the level of sperm abnormalities and fertilizing capacity are determined
largely autonomously by genes acting in the germ cells. (Krzanowska et al 1991
A. and Krzanowska H. (1972) Spermatogenesis in mouse strains with high
and low abnormal spermatazoa. J. Hered. 63, 172-174.
H., Wabik-Sliz B., and Rafinski J. (1991) Phenotype and fertilizing capacity
of spermatozoa of chimaeric mice produced from two strains that differ
in sperm quality. J. Reprod. Fertil. 91, 667-676.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,