Inbred Strains
of Mice: JU
Inbr: F41+60 (Ct). Albino. Genet:
a, c. Origin: Falconer 1952,
from crosses involving Goodale's and MacArthur's large strains, Bateman's
high-lactation strain and various mutant stocks with about 50% of C57BL/Fa
ancestry. It was the only survivor from an inbreeding experiment involving
twenty lines (Falconer, 1960b). Falconer to Cattanach in 1966.
Characteristics
Average first litters 9; high prenatal mortality (50%) in second litters
when gestation is concurrent with suckling first litter; low penetrance
of
nil. (
Staats, 1976). Lm maintains
a number of substrains with different pigment mutations including a non-albino
+c . Maint. by Ct.
JU/Ct-C.
Inbr. N5F59 (Ct). Black,
a,
C. Derived from a cross between
JU female (F41) with a CBA male, five backcrosses to JU, then selection
for the
CC genotype upon sib mating.
JU/Ct-C,A.
Inbr. N5F59. Agouti, +. Origin: same as JU/Ct-
C, but selection
for the agouti phenotype upon sib mating. Charac. Background enhances
expression of
Sl and
Wv with
regard to coat colour.
Staats J. (1976) Standardized
nomenclature for inbred strains of mice: Sixth listing. Cancer Res.
36, 4333-4377.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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