of Mice: BL
Inbr: F108. Albino. Genet: a, b, c
strain developed by Lynch from
Bagg albino stock via Strong, and maintained at Rockefeller Institute
Low mammary tumours, some lung tumours in older mice (Staats,
). Ovaries often appear pale and enlarged and have an infiltration
of amyloid. Thought to be due to necrotising arteritis in which there
is a thickening of the walls of the vessels to duodenum and ovaries due
to a deposition of eosinophilic material within the intima and media (Deringer, 1959b
). Aseptic necrosis of bone in
22% of females often resulting in fracture of femoral neck and other complications,
so that the animals are severely crippled (Sokoloff
and Haberman, 1958
K. (1959b) Occurrence of tumors, particularly mammary tumors in agent-free
strain C3HeB mice. J. Natl. Cancer Inst. 22, 995-1002.
L. and Haberman R. T. (1958) Idiopathic necrosis of bone in small animals.
Arch. Pathol. 65, 323-330.
Staats J. (1976) Standardized
nomenclature for inbred strains of mice: Sixth listing. Cancer Res.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,