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101

INBRED STRAINS AND THEIR CHARACTERISTICS

Inbr: 66. Genet: A^w . Origin: Dunn, 1936.

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Characteristics

Low mammary tumour incidence; slow to breed, fertility moderate; high susceptibility to skin and lung tumour induction. Low metabolic rate (6/6) (Pennycuik, 1967). Resistant to Mycobacterium marinum (1/9) (Shepard and Habas, 1967). Unusual backward locomotion observed in 101/HY, somewhat similar to the hot-foot neurological mutation (Poletaeva et al 1992). Maint. by H.

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Pennycuik P. R. (1967) A comparison of the effects of a variety of factors on the metabolic rate of the mouse. Aust. J. Biol. Med. Sci. 45, 331-346. \par

Poletaeva I. I., Lilp I. G., Irisova O. A., Ivanov V. I., and Bizikoeva F. Z. (1992) An unusual type of locomotion in mice of line 101/Hy [Russian]. Genetika 28, 147-149. \par

Shepard C. C. and Habas J. A. (1967) Relation of infection to tissue temperature in mice infected with Mycobacterium marinum and Mycobacterium leprae. J. Bacteriol. 93, 790-796. \par

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK