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Symbol
Name
ID

Irs1
insulin receptor substrate 1
MGI:99454

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Increased waist to hip ratio	Obesity
Disease(s) Associated with IRS1	Increased waist to hip ratio	Obesity
coronary artery disease
type 2 diabetes mellitus

Mouse Phenotypes		decreased birth weight	decreased body weight	abnormal postnatal growth/weight/body size	decreased body length	decreased body size	proportional dwarf	postnatal growth retardation	decreased fetal weight	fetal growth retardation
Availability	Mouse Genotype	decreased birth weight	decreased body weight	abnormal postnatal growth/weight/body size	decreased body length	decreased body size	proportional dwarf	postnatal growth retardation	decreased fetal weight	fetal growth retardation
	Irs1^m1Btlr/Irs1^m1Btlr
	Irs1^m2Btlr/Irs1^m2Btlr
	Irs1^mpc178H/Irs1^mpc178H
	Irs1^Sml/Irs1^Sml
	Irs1^smla/Irs1^smla
	Irs1^tm1Jos/Irs1^tm1Jos
	Irs1^tm1Tka/Irs1^tm1Tka
	Irs1^tm2.1Mfw/Irs1^tm2.1Mfw
	Irs1^Sml/Irs1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23