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Symbol
Name
ID

Nhlh2
nescient helix loop helix 2
MGI:97324

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased serum testosterone concentration
Disease(s) Associated with NHLH2	Decreased serum testosterone concentration
hypogonadotropic hypogonadism

Mouse Phenotypes		homeostasis/metabolism phenotype	decreased circulating testosterone level	decreased circulating estradiol level	decreased circulating follicle stimulating hormone level	increased circulating alanine transaminase level	increased circulating aspartate transaminase level	decreased core body temperature	impaired glucose tolerance	abnormal cholesterol homeostasis
Availability	Mouse Genotype	homeostasis/metabolism phenotype	decreased circulating testosterone level	decreased circulating estradiol level	decreased circulating follicle stimulating hormone level	increased circulating alanine transaminase level	increased circulating aspartate transaminase level	decreased core body temperature	impaired glucose tolerance	abnormal cholesterol homeostasis
	Nhlh2^em1(IMPC)Mbp/Nhlh2^em1(IMPC)Mbp
	Nhlh2^{tm1b(KOMP)Mbp}/Nhlh2^{tm1b(KOMP)Mbp}
	Nhlh2^tm1Irk/Nhlh2^tm1Irk	*
	Nhlh2^tm2Thbr/Nhlh2^tm2Thbr Tg(CMV-cre)1Cgn/0 (conditional)
	Nhlh2^tm2Thbr/Nhlh2^tm2Thbr Tg(Gnrh1-cre)1Dlc/0 Tg(Pomc-EGFP)1Low/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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