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Symbol
Name
ID

Mertk
MER proto-oncogene tyrosine kinase
MGI:96965

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes	Optic disc pallor	Macular atrophy	Peripheral retinal atrophy	Rod-cone dystrophy	Nyctalopia	Constriction of peripheral visual field	Progressive visual loss
Disease(s) Associated with MERTK
retinitis pigmentosa 38

Mouse Phenotypes

abnormal retina vasculature morphology

increased retina apoptosis

decreased retina photoreceptor cell number

abnormal photoreceptor outer segment morphology

disorganized photoreceptor outer segment

photoreceptor outer segment degeneration

retina rod cell degeneration

retina photoreceptor degeneration

abnormal retina pigment epithelium morphology

abnormal retina pigmentation

retina pigment epithelium atrophy

abnormal retina morphology

abnormal retina outer nuclear layer morphology

thin retina outer nuclear layer

abnormal retina photoreceptor layer morphology

decreased total retina thickness

retina degeneration

abnormal eye electrophysiology

abnormal cone electrophysiology

abnormal rod electrophysiology

blindness

Availability

Mouse Genotype

Mertk^nmf12/Mertk^nmf12

Mertk^tm1Gkm/Mertk^tm1Gkm

Mertk^tm1Grl/Mertk^tm1Grl

Mertk^nmf12/Mertk^tm1Gkm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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