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Symbol
Name
ID
Irf8
interferon regulatory factor 8
MGI:96395
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Abnormal circulating IgG level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Hypercalcemia
Elevated circulating creatinine concentration
Hypoalbuminemia
Hyperproteinemia
Pleural effusion
Fever
Abnormality of vitamin B12 metabolism
Hematuria
Pyuria
Decreased level of D-mannose in urine
Proteinuria
Amyloidosis
Cerebral calcification
Disease(s) Associated with IRF8
Behcet's disease
immunodeficiency 32A
immunodeficiency 32B
multiple myeloma
systemic lupus erythematosus

Mouse Phenotypes
decreased fasting circulating glucose level
decreased circulating free fatty acids level
increased circulating sodium level
increased circulating total protein level
Availability Mouse Genotype
Irf8tm1b(KOMP)Wtsi/Irf8tm1b(KOMP)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory