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Symbol
Name
ID 		Ctla4
cytotoxic T-lymphocyte-associated protein 4
MGI:88556
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Alopecia of scalp
Xanthelasma
Breast carcinoma
Erythema
Facial erythema
Dermatographic urticaria
Jaundice
Fasciitis
Inflammatory abnormality of the skin
Eczematoid dermatitis
Atopic dermatitis
Erythema nodosum
Recurrent skin infections
Chronic intestinal candidiasis
Discoid lupus rash
Maculopapular exanthema
Malar rash
Patchy alopecia
Alopecia
Alopecia totalis
Alopecia universalis
Nail pits
Trachyonychia
Onycholysis
Hyperhidrosis
Abnormality of the skin
Abnormal skin morphology
Scaling skin
Hyperpigmentation of the skin
Hypopigmentation of the skin
Vitiligo
Dry skin
Cutaneous photosensitivity
Keratosis pilaris
Flexural lichenification
Lichenoid skin lesion
Nevus
Skin erosion
Skin nodule
Subcutaneous nodule
Skin plaque
Cutaneous sclerotic plaque
Skin ulcer
Pallor
Pretibial myxedema
Ichthyosis
Pruritus
Disease(s) Associated with CTLA4
alopecia areata
atopic dermatitis
Behcet's disease
breast cancer
graft-versus-host disease
granulomatosis with polyangiitis
Graves' disease
immunoglobulin alpha deficiency
primary biliary cholangitis
sarcoidosis
systemic lupus erythematosus
vitiligo

Mouse Phenotypes
variable depigmentation
Availability Mouse Genotype
Ctla4tm1All/Ctla4tm1All
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory