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Symbol
Name
ID

Asl
argininosuccinate lyase
MGI:88084

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased circulating argininosuccinic acid	Hypoargininemia	Hyperglutaminemia	Hyperammonemia	Episodic ammonia intoxication	Elevated CSF argininosuccinic acid concentration	Elevated circulating aspartate aminotransferase concentration	Respiratory alkalosis	Cerebral edema	Oroticaciduria	Aminoaciduria
Disease(s) Associated with ASL
argininosuccinic aciduria

Mouse Phenotypes		homeostasis/metabolism phenotype	decreased circulating arginine level	abnormal circulating amino acid level	increased circulating citrulline level	increased circulating glutamine level	increased circulating ammonia level	decreased circulating alanine transaminase level	decreased circulating aspartate transaminase level	abnormal nitric oxide homeostasis	abnormal enzyme/coenzyme activity
Availability	Mouse Genotype	homeostasis/metabolism phenotype	decreased circulating arginine level	abnormal circulating amino acid level	increased circulating citrulline level	increased circulating glutamine level	increased circulating ammonia level	decreased circulating alanine transaminase level	decreased circulating aspartate transaminase level	abnormal nitric oxide homeostasis	abnormal enzyme/coenzyme activity
	Asl^tm1Brle/Asl^tm1Brle
	Asl^tm1Wjc/Asl^tm1Wjc	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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