Symbol
Name
ID

Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
MGI:87888

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

behavior/neurological phenotype

abnormal behavioral response to addictive substance

enhanced behavioral response to nicotine

impaired behavioral response to nicotine

impaired behavioral response to addictive substance

increased susceptibility to pharmacologically induced seizures

enhanced conditioned place preference behavior

impaired conditioned place preference behavior

abnormal motor learning

abnormal response to new environment

increased exploration in new environment

abnormal emotion/affect behavior

increased anxiety-related response

decreased grooming behavior

abnormal locomotor activation

increased vertical activity

behavioral arrest

decreased chemically-elicited antinociception

seizures

clonic seizures

Availability

Mouse Genotype

Chrna4^tm1.1Stit/Chrna4^tm1.1Stit

Chrna4^tm1.2Tmcg/Chrna4^tm1.2Tmcg

Chrna4^tm1Dra/Chrna4^tm1Dra

Chrna4^tm1Jbou/Chrna4^tm1Jbou

Chrna4^tm1Jpc/Chrna4^tm1Jpc

Chrna4^tm2Jbou/Chrna4^tm2Jbou

Chrna4^tm2Lst/Chrna4^tm2Lst

Chrna4^tm1Jbou/Chrna4⁺

Chrna4^tm1Lst/Chrna4⁺

Chrna4^tm2.1Dra/Chrna4⁺

Chrna4^tm2Jbou/Chrna4⁺

Chrna4^tm1.1Tmcg/Chrna4^tm1.1Tmcg
Slc6a3^tm1(cre)Xz/Slc6a3⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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