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Symbol
Name
ID
Chd7
chromodomain helicase DNA binding protein 7
MGI:2444748
Phenotype annotations related to embryo
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Polyhydramnios
Disease(s) Associated with CHD7
CHARGE syndrome

Mouse Phenotypes
embryo phenotype
abnormal pharyngeal arch artery morphology
abnormal fourth pharyngeal arch artery morphology
abnormal sixth pharyngeal arch artery morphology
abnormal neural crest cell migration
delayed embryo turning
embryonic growth arrest
embryonic growth retardation
abnormal embryonic neuroepithelium morphology
decreased embryonic neuroepithelium thickness
Availability Mouse Genotype
Chd7em1Jiao/Chd7em1Jiao
Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor
Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi
Chd7Coa1/Chd7+
Chd7Gt(RRR136)Byg/Chd7+
Chd7Gt(S20-7E1)Sor/Chd7+
Chd7Gt(XK403)Byg/Chd7+
Chd7Gt(XK403)Byg/Chd7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Chd7Gt(XK403)Byg/Chd7+
Tg(Tbx1-cre)1Joe/0  (conditional)
Chd7Gt(XK403)Byg/Chd7+
Mesp1tm2(cre)Ysa/Mesp1+  (conditional)
Chd7Gt(XK403)Byg/Chd7+
Tfap2atm1(cre)Moon/Tfap2a+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory