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Symbol
Name
ID
Wwox
WW domain-containing oxidoreductase
MGI:1931237
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Cerebral calcification
Disease(s) Associated with WWOX
developmental and epileptic encephalopathy 28

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal homeostasis
increased blood urea nitrogen level
increased blood uric acid level
decreased circulating bicarbonate level
increased circulating bilirubin level
decreased circulating glucose level
hypoglycemia
decreased circulating testosterone level
decreased circulating cholesterol level
decreased circulating triglyceride level
decreased circulating calcium level
increased circulating phosphate level
increased circulating potassium level
decreased circulating sodium level
abnormal circulating enzyme level
decreased circulating alkaline phosphatase level
decreased circulating aspartate transaminase level
decreased circulating serum albumin level
decreased circulating total protein level
decreased circulating chloride level
increased circulating chloride level
increased incidence of tumors by chemical induction
Availability Mouse Genotype
Wwoxem1Mald/Wwoxem1Mald *
Wwoxtm1.1Mald/Wwoxtm1.1Mald
Wwoxtm1Ria/Wwoxtm1Ria
Wwoxtm2.1Ria/Wwoxtm2.1Ria
Wwoxtm1Ria/Wwox+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory