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Symbol
Name
ID 		Trps1
transcriptional repressor GATA binding 1
MGI:1927616
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Sparse scalp hair
Micrognathia
Chin with horizontal crease
Deep philtrum
Long philtrum
Smooth philtrum
Thin upper lip vermilion
Narrow palate
Microdontia
Supernumerary tooth
Delayed eruption of teeth
Carious teeth
Dental crowding
Dental malocclusion
Underdeveloped nasal alae
Bulbous nose
Pear-shaped nose
Sparse lateral eyebrow
Thin eyebrow
Disease(s) Associated with TRPS1
trichorhinophalangeal syndrome type I
trichorhinophalangeal syndrome type III

Mouse Phenotypes
abnormal basicranium morphology
small basisphenoid bone
abnormal cranial cartilage development
absent presphenoid bone
zygomatic arch hypoplasia
abnormal dental pulp cavity morphology
abnormal incisor morphology
abnormal dentin mineralization
delayed tooth eruption
abnormal dentin morphology
brittle teeth
abnormal mandibular angle morphology
mandibular condyloid process hypoplasia
mandibular coronoid process hypoplasia
short mandible
maxillary zygomatic process hypoplasia
short maxilla
micrognathia
vomer bone hypoplasia
abnormal secondary palate development
delayed palatal shelf elevation
palatal shelves fail to meet at midline
arched palate
cleft palate
abnormal nose morphology
abnormal nasal septum morphology
downturned snout
short snout
Availability Mouse Genotype
Trps1tm1.1Shiv/Trps1tm1.1Shiv
Trps1tm1Ymur/Trps1tm1Ymur
Trps1tm1.1Shiv/Trps1+
Tg(Tyr,Col1a1-Trps1)1Brle/0
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory