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Symbol
Name
ID

Tfr2
transferrin receptor 2
MGI:1354956

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abnormality of iron homeostasis	Increased circulating iron concentration	Elevated transferrin saturation	Increased circulating ferritin concentration	Elevated circulating hepatic transaminase concentration	Hypoglycemia	Nonimmune hydrops fetalis
Disease(s) Associated with TFR2	Abnormality of iron homeostasis	Increased circulating iron concentration	Elevated transferrin saturation	Increased circulating ferritin concentration	Elevated circulating hepatic transaminase concentration	Hypoglycemia	Nonimmune hydrops fetalis
hemochromatosis
hemochromatosis type 3

Mouse Phenotypes		homeostasis/metabolism phenotype	decreased spleen iron level	increased spleen iron level	increased circulating iron level	increased circulating ferritin level	abnormal iron homeostasis	increased liver iron level	hemochromatosis
Availability	Mouse Genotype	homeostasis/metabolism phenotype	decreased spleen iron level	increased spleen iron level	increased circulating iron level	increased circulating ferritin level	abnormal iron homeostasis	increased liver iron level	hemochromatosis
	Tfr2^{em1(IMPC)Rbrc}/Tfr2^{em1(IMPC)Rbrc}
	Tfr2^m1Btlr/Tfr2^m1Btlr
	Tfr2^tm1.1Anro/Tfr2^tm1.1Anro	*
	Tfr2^tm1.1Nsub/Tfr2^tm1.1Nsub
	Tfr2^tm1Slu/Tfr2^tm1Slu
	Tg(Alb1-cre)7Gsc/0 Tfr2^tm1.1Anro/Tfr2^tm1.1Anro (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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