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Symbol Name ID |
Ikbkg
inhibitor of kappaB kinase gamma MGI:1338074 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Reduced natural killer cell activity |
Increased circulating IgA level |
Abnormal circulating IgG level |
Decreased circulating total IgM |
Increased circulating IgM level |
Dysgammaglobulinemia |
Lymphedema |
Decreased level of D-mannose in urine |
Scarring |
| Disease(s) Associated with IKBKG | |||||||||
| Behcet's disease | |||||||||
| Bloch-Sulzberger syndrome | |||||||||
| ectodermal dysplasia and immunodeficiency 1 | |||||||||
| immunodeficiency 33 |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased circulating glucose level |
increased circulating tumor necrosis factor level |
increased circulating alanine transaminase level |
increased circulating aspartate transaminase level |
increased circulating glutamate dehydrogenase level |
abnormal enzyme/coenzyme activity |
abnormal response/metabolism to endogenous compounds |
decreased susceptibility to xenobiotic induced morbidity/mortality |
increased susceptibility to xenobiotic induced morbidity/mortality |
decreased physiological sensitivity to xenobiotic |
increased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||||||||||
| Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr Tg(Alb1-cre)7Gsc/0 (conditional) |
* | ||||||||||||
| Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa Tg(Alb1-cre)7Gsc/0 (conditional) |
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| Ikbkgtm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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