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Symbol
Name
ID

Dnmt3b
DNA methyltransferase 3B
MGI:1261819

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Micrognathia	Sinusitis	Malar flattening	Flat face	Weakness of facial musculature	Macroglossia	Protruding tongue	Anteverted nares	Depressed nasal bridge	Short nose	Epicanthus
Disease(s) Associated with DNMT3B	Micrognathia	Sinusitis	Malar flattening	Flat face	Weakness of facial musculature	Macroglossia	Protruding tongue	Anteverted nares	Depressed nasal bridge	Short nose	Epicanthus
facioscapulohumeral muscular dystrophy 4
immunodeficiency-centromeric instability-facial anomalies syndrome 1

Mouse Phenotypes

abnormal craniofacial morphology

abnormal cranium morphology

large anterior fontanelle

enlarged frontal bone

wide frontal bone

enlarged interparietal bone

abnormal nasal bone morphology

short nasal bone

abnormal facial morphology

cleft palate

short snout

Availability

Mouse Genotype

Dnmt3b^em1(IMPC)Mbp/Dnmt3b^em1(IMPC)Mbp

Dnmt3b^tm6Enl/Dnmt3b^tm6Enl

Dnmt3b^tm1.1Ics/Dnmt3b^tm2.1Ics

Dnmt3b^tm6Enl/Dnmt3b^tm7Enl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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