Symbol
Name
ID

Krt6a
keratin 6A
MGI:1100845

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Palmoplantar blistering

Palmoplantar hyperhidrosis

Plantar hyperkeratosis

Palmoplantar keratoderma

Palmar hyperkeratosis

Alopecia

Fingernail dysplasia

Paronychia

Nail dystrophy

Onychogryposis of fingernail

Onychogryposis of toenails

Epidermal acanthosis

Cutaneous cyst

Epidermoid cyst

Eruptive vellus hair cyst

Follicular hyperkeratosis

Linear arrays of macular hyperkeratoses in flexural areas

Steatocystoma multiplex

Disease(s) Associated with KRT6A

pachyonychia congenita

Disease(s) Associated with KRT6B

pachyonychia congenita

Disease(s) Associated with KRT6C

focal or diffuse nonepidermolytic palmoplantar keratoderma

Mouse Phenotypes		integument phenotype	abnormal hair growth	abnormal keratinocyte morphology
Availability	Mouse Genotype	integument phenotype	abnormal hair growth	abnormal keratinocyte morphology
	Krt6a/Krt6b^tm1Cou/Krt6a/Krt6b^tm1Cou	*
	Tg(Krt2-6a)1Der/0
	Tg(Krt2-6a)3Der/0
	Tg(Krt2-6a)4Der/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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