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Symbol
Name
ID
Fzd4
frizzled class receptor 4
MGI:108520
Phenotype annotations related to vision/eye
Darker colors indicate more annotations
Human Phenotypes
Vitreous hemorrhage
Peripheral retinal avascularization
Retinal neovascularization
Subcapsular cataract
Retinal detachment
Falciform retinal fold
Retinal exudate
Posterior vitreous detachment
Exudative vitreoretinopathy
Reduced visual acuity
Blindness
Disease(s) Associated with FZD4
exudative vitreoretinopathy 1

Mouse Phenotypes
impaired pupillary reflex
abnormal retinal vasculature morphology
retinal hemorrhage
abnormal eye morphology
persistence of hyaloid vascular system
microphthalmia
abnormal eye electrophysiology
Availability Mouse Genotype
Fzd4tm1Nat/Fzd4tm1Nat
Fzd4tm1.1(KOMP)Vlcg/Fzd4+
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(Tek-cre)1Ywa/?  (conditional)
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(rx3-icre)1Mjam/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory