|
Symbol Name ID |
Ifng
interferon gamma MGI:107656 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating IgG2 level |
Defective B cell differentiation |
Abnormality of chromosome stability |
Chromosome breakage |
Hyperbilirubinemia |
Elevated circulating alpha-fetoprotein concentration |
Elevated circulating C-reactive protein concentration |
Increased circulating ferritin concentration |
Elevated circulating hepatic transaminase concentration |
Elevated circulating alkaline phosphatase concentration |
Elevated erythrocyte sedimentation rate |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Joint swelling |
Fever |
Hematuria |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Decreased thyroid-stimulating hormone level |
Increased circulating cortisol level |
Cerebral calcification |
| Disease(s) Associated with IFNG | |||||||||||||||||||||||||
| ataxia telangiectasia | |||||||||||||||||||||||||
| chronic granulomatous disease | |||||||||||||||||||||||||
| factor VIII deficiency | |||||||||||||||||||||||||
| graft-versus-host disease | |||||||||||||||||||||||||
| Graves' disease | |||||||||||||||||||||||||
| immunodeficiency 69 | |||||||||||||||||||||||||
| rheumatoid arthritis | |||||||||||||||||||||||||
| systemic scleroderma | |||||||||||||||||||||||||
| temporal arteritis | |||||||||||||||||||||||||
| tuberous sclerosis 2 | |||||||||||||||||||||||||
| type 2 diabetes mellitus | |||||||||||||||||||||||||
| vesicoureteral reflux |
| Mouse Phenotypes | abnormal circulating cytokine level |
abnormal circulating interferon level |
increased circulating interleukin-12 level |
increased circulating interleukin-6 level |
abnormal circulating enzyme level |
increased circulating alanine transaminase level |
ascites |
abnormal nitric oxide homeostasis |
abnormal cytokine level |
abnormal urine homeostasis |
albuminuria |
increased susceptibility to xenobiotic induced morbidity/mortality |
decreased physiological sensitivity to xenobiotic |
abnormal response to injury |
decreased susceptibility to injury |
|
| Availability | Mouse Genotype | |||||||||||||||
| Ifngtm1.1Hayg/Ifngtm1.1Hayg | ||||||||||||||||
| Ifngtm1Ts/Ifngtm1Ts | ||||||||||||||||
| Ifngtm1Yiw/Ifngtm1Yiw | ! | |||||||||||||||
| Tg(APCS-Ifng)5Imeg/0 | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools