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Symbol
Name
ID
Myh11
myosin, heavy polypeptide 11, smooth muscle
MGI:102643
Phenotype annotations related to muscle
Darker colors indicate more annotations
Human Phenotypes
Gastroparesis
Disease(s) Associated with MYH11
megacystis-microcolon-intestinal hypoperistalsis syndrome

Mouse Phenotypes
dilated cardiomyopathy
abnormal vascular smooth muscle physiology
increased vascular smooth muscle cell proliferation
decreased vasoconstriction
intestinal hypoperistalsis
abnormal sarcomere morphology
abnormal muscle contractility
impaired smooth muscle contractility
impaired contractility of urinary bladder detrusor smooth muscle
Availability Mouse Genotype
Myh11tm1.1Dmmz/Myh11tm1.1Dmmz
Myh11tm1Bdr/Myh11tm1Bdr
Myh11tm1Peri/Myh11tm1Peri
Myh11tm2Peri/Myh11tm2Peri
Myh11tm1Peri/Myh11+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory