Alpha-Thalassemia MGI Mouse Model Detail

Human Disease and Mouse Model Detail

Human Disease

Alpha-Thalassemia
OMIM ID: 604131

View all models

View ALL (7) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Hba-a1, Hba-a2	HBA1, HBA2**		2:2 Homology
Hbb-bs, Hbb-bt	HBB*		2:1 Homology

Transgenes and
other genome features

Transgenes and other genome features developed in mice to model this disease.

	Transgenes and Other Genome Features	Mouse Models
	Hba	View 7 models

References

Disease References using Mouse Models (4)

Mouse Models

Human Disease Modeled: Alpha-Thalassemia
Associated Mouse Complex/Cluster/Region: Hba

Allelic Composition	Genetic Background	Reference	Phenotypes
Hbab2(th)/Hba+	either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	J:123943	View
Hbab3(th)/Hba+	either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	J:123943	View
Hbath-J/Hba+	involves: C57BL/6J	J:45721, J:32654	View
Hbab2(th)/Hba+	involves: C57BL6J * SEC	J:32654	View
Hbab3(th)/Hba+	involves: C57BL6J * SEC	J:32654	View
Hbab2(th)/Hba+	SEC-Hba^b2(th)	J:6452	View
Hbab3(th)/Hba+	SEC-Hba^b3(th)	J:6452	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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