Alpha-Thalassemia MGI Mouse Model Detail

Human Disease and Mouse Model Detail

Human Disease

Alpha-Thalassemia
OMIM ID: 604131
Human Phenotype Ontology associations

View all models

View ALL (7) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

Disease is associated/modeled with this Gene* or a homolog. More...
Human Homologs	Mouse Homologs	Mouse Models	Homology Source
HBA1, HBA2**	Hba-a1, Hba-a2		HomoloGene and HGNC
HBB*	Hbb-bs, Hbb-bt		HomoloGene and HGNC

Transgenes and
other genome features

Transgenes and other genome features developed in mice to model this disease.

	Transgenes and Other Genome Features	Mouse Models
	Hba	View 7 models

References

Disease References using Mouse Models (4)

Allelic Composition	Genetic Background	Reference	Phenotypes
Hbab2(th)/Hba+	either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	J:123943	View
Hbab3(th)/Hba+	either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC)	J:123943	View
Hbath-J/Hba+	involves: C57BL/6J	J:45721, J:32654	View
Hbab2(th)/Hba+	involves: C57BL6J * SEC	J:32654	View
Hbab3(th)/Hba+	involves: C57BL6J * SEC	J:32654	View
Hbab2(th)/Hba+	SEC-Hba^b2(th)	J:6452	View
Hbab3(th)/Hba+	SEC-Hba^b3(th)	J:6452	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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