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Disease Ontology Browser
mal de Meleda (DOID:0060862)
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Synonyms: keratosis palmoplantaris transgrediens of Siemens; Meleda disease; transgrediens palmoplantar keratoderma of Siemens
Alt IDs: OMIM:248300, ICD10CM:Q82.8, ORDO:87503
Definition: A palmoplantar keratosis characterized by autosomal recessive inheritance of symmetric palmoplantar hyperkeratosis that progressively extends to the dorsal surfaces of hands and feet and ichthyotic changes elsewhere that has material_basis_in homozygous mutation in the SLURP1 gene on chromosome 8q24.

Disease References using Mouse Models (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory